The ASPIS chemical selection working group is co-chaired by Drs. Mathieu Vinken (ONTOX) and Jonathan Freedman (PrecisionTox).
The CSWG includes members from the three consortia, as well as the Joint Research Centre. The goal of this working group is to coordinate chemical selection among the ASPIS partners. Through this coordinated effort, the CSWG plans to minimize duplication of efforts, compound purchasing and identify inter-consortia activities. Additionally, the CSWG is involved in the development of ASPIS-wide case studies, communication and assisting other working groups. To accomplish these goals, the CSWG has established two sub-working groups: Database and AI Selection. The Database group, led by Dr Barry Hardy (RiskHunt3r), is responsible for creating an ASPIS-wide chemical database. This database will initially contain information on physicochemical characteristics and toxicological information on chemicals used by ASPIS. In the future, it can become a central resource of the data generated by three consortia.
The intended users of this database will include basic scientists, as well as members of ASPIS involved in risk assessment/policy, communication, and computational approaches. Ultimately this database will be made available to the general public. The AI selection group, led by Dr. Marc Teunis (ONTOX) is developing cutting-edge technologies to mine the literature for toxicological information. This information will then be included in the database.