The ASPIS chemical selection working group (CSWG) is co-chaired by Prof. Mathieu Vinken (ONTOX) and Prof. Jonathan Freedman (PrecisionTox).
The CSWG includes members from the three consortia and the Joint Research Centre. This working group aims to coordinate chemical selection among the ASPIS partners. Through this coordinated effort, the CSWG plans to minimise duplication of efforts, compound purchasing and identify inter-consortia activities.
Additionally, the CSWG is involved in developing ASPIS-wide case studies and communication and assisting other working groups. The CSWG has established two sub-working groups to accomplish these goals: Database and AI Selection.
The sub-working groups evolved into the new ASPIS Database working group (DbWG) that addresses database needs beyond chemical selection/chemo information and develops and deploys related biological and toxicological knowledge. It will expand the ASPIS database to form an international chemical knowledge resource supporting predictive toxicology, risk assessment guidance, policy development, communication and computational approaches.
Chemical selection can be an essential component in developing NAMs and NGRA. Therefore, CSWG works closely with the ASPIS Risk Assessment, Computational Approaches and qAOP working group.